Anupa Geethadevi

This study shows that corin, a CoREST inhibitor, reduces ATRT tumor growth, increases differentiation, and extends lifespan in xenograft models.

This study shows that mirdametinib and abemaciclib reduce ATRT cell proliferation and extend mouse survival when used together.

The paper shows that inhibiting the CoREST complex with corin alters RNA splicing, increases neoantigen expression, and enhances tumor immunity in melanoma.