Intrahippocampal delivery of hyperphosphorylated human tau oligomers induces neurodegeneration in non-transgenic wildtype mice
Hong‐Ru Chen, Hsiao‐Tien Chien Hagar, Kuan-Wei Wang…·Chia-Yi Kuan
The paper investigates the role of hyperphosphorylated tau oligomers in inducing neurodegeneration by injecting them into non-transgenic mice, finding cognitive deficits and neuron death.