Author

Mackenzie M. Spicer

University of IowaORCID 0000-0001-8106-0862Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Matthew A. WeberiD· 3 shared Nandakumar S. NarayananiD· 3 shared Alexandra S. BovaiD· 2 shared Jianqi Yang· 2 shared Madison S. McMurriniD· 2 shared Rory Alan FisheriD· 2 shared Alison N. DeVoreiD· 1 shared Braedon Q Kirkpatrick· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Matthew A. WeberORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeuroscienceJournal of NeurosciencePeer-reviewedApr 17, 2026

Timing, movement, and reward contributions to prefrontal and striatal ramping activity

Alexandra S. Bova, Matthew A. Weber, Mackenzie M. Spicer…·Nandakumar S. Narayanan

This study investigates how time estimation, movement, and reward anticipation contribute to prefrontal and striatal ramping activity in mice during interval timing tasks.

3 citationstop 5%

mouseelectronic health records

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NeurosciencebioRxivPreprintMay 12, 2025

Diverse activity in prefrontal projections promotes temporal control of action

Xin Ding, Matthew A. Weber, Trevor C. Butler…·Nandakumar S. Narayanan

The paper investigates prefrontal projections during interval timing, finding distinct temporal coding and transcriptomic profiles in PFC-MD and PFC-DMS circuits.

3 citations

humanmouse

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 24, 2023

Regulator of G protein signaling 6 (RGS6) in ventral tegmental area (VTA) dopamine neurons promotes EtOH seeking, behavioral reward and susceptibility to relapse

Mackenzie M. Spicer, Matthew A. Weber, Zili Luo…·Rory Alan Fisher

This study shows that RGS6 in VTA dopamine neurons promotes EtOH seeking, reward, and relapse by enhancing DA transmission through GPCR-Gi/o-DAT signaling.

1 citation

mousehuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 17, 2023

RGS6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in an Alzheimer's mouse model

Mackenzie M. Spicer, Jianqi Yang, Daniel Fu…·Rory Alan Fisher

This paper shows that RGS6 in hippocampal neural progenitors mediates exercise-induced recovery of neurogenesis and cognition in Alzheimer's mice.

3 citations

mouseexperimental assay

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