Regulator of G protein signaling 6 (RGS6) in ventral tegmental area (VTA) dopamine neurons promotes EtOH seeking, behavioral reward and susceptibility to relapse
Mackenzie M. Spicer, Matthew A. Weber, Zili Luo, Jianqi Yang, Nandakumar S. Narayanan, Rory Alan Fisher
This study shows that RGS6 in VTA dopamine neurons promotes EtOH seeking, reward, and relapse by enhancing DA transmission through GPCR-Gi/o-DAT signaling.
bioRxiv · Oct 24, 2023 · PreprintNeuroscience