Cell BiologyNature CommunicationsPeer-reviewed
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling
Cristiana C Santos, Nadine Schweizer, Fátima Cairrão…·Pedro Manuel Dias Neto Domingos
This study shows Fbxo42 promotes degradation of Ataxin-2 granules, enabling Xbp1 translation and triggering cell death during terminal UPR activation.
7 citations