Author

Nadine Schweizer

Instituto de Tecnologia Química e Biológica António XavierORCID 0000-0002-8701-2690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Ana Montaño-RodrigueziD· 1 shared Anne E. PanhelaineniD· 1 shared Catarina J GaspariD· 1 shared Colin AdrainiD· 1 shared Cristiana C SantosiD· 1 shared Daniel R. GartoniD· 1 shared Fátima CairrãoiD· 1 shared Franka VoigtiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Ana Montaño-RodriguezORCID

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2 papers

Recent·Most cited

Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling

Cristiana C Santos, Nadine Schweizer, Fátima Cairrão, Juanma Ramírez, Nerea Osinalde, Ming Yang, Catarina J Gaspar, Vanya I Rasheva, Miguel L Trigo, Zach Hensel, Colin Adrain, Tiago N. Cordeiro, Franka Voigt, Paulo A. Gameiro, Ugo Mayor, Pedro Manuel Dias Neto Domingos

This study shows Fbxo42 promotes degradation of Ataxin-2 granules, enabling Xbp1 translation and triggering cell death during terminal UPR activation.

Nature Communications · Aug 13, 2025Peer-reviewedCell Biology

Gene Knock Up via 3’UTR editing to study gene function in vivo

Kärt Mätlik, Soophie Olfat, Daniel R. Garton, Ana Montaño-Rodriguez, Giorgio Turconi, L. Lauriina Porokuokka, Anne E. Panhelainen, Nadine Schweizer, Jaakko J. Kopra, Mark Cary Cowlishaw, Petteri T. Piepponen, Fuping Zhang, Petra Sipilä, Johan Jakobsson, Jaan‐Olle Andressoo

This paper develops methods to upregulate gene expression in vivo while preserving cell-type-specific regulation, demonstrating their use in studying gene function and disease mechanisms.

bioRxiv · Sep 23, 2019 · PreprintNeuroscience