Petra Sipilä

The paper shows that fetal testosterone deficiency reduces adult male kidney size in mice by affecting growth pathways.

This paper generates a Cln8 p.R24G mouse model that phenocopies major clinical features of Northern epilepsy, including seizures and neurodegeneration.

This study investigates the role of GLE1 in cellular homeostasis and development, showing that its dysfunction leads to embryonic lethality and mid-adulthood death in mice, with defects in neural crest-derived tissues and stress responses.

This study shows that Parp14 deficiency in mice worsens colitis by impairing epithelial barrier integrity and altering inflammation-related gene expression.

This paper develops methods to upregulate gene expression in vivo while preserving cell-type-specific regulation, demonstrating their use in studying gene function and disease mechanisms.