Anthony Nash

This study uses prescription analgesic use data to identify 140 genetic associations with chronic pain, including 78 novel loci, and suggests new biological mechanisms.

This paper presents a drug-design framework targeting substrate-specific allosteric sites on collagen-bound MMP1 using MD simulations, conformational clustering, and machine learning, identifying compounds that preferentially bind around R405.

This paper shows collagen affects MMP1 dynamics, allostery, and ligand binding through MD simulations and virtual screening, revealing substrate-specific allosteric residues and potential drug targets.

The paper introduces an R package for analyzing drug prescriptions in electronic health care records to extract demographic and patient-level characteristics.