Author

Dhanoop Manikoth Ayyathan

University Health NetworkORCID 0000-0001-8214-1381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron David SchimmeriD· 1 shared Abdula MaheriD· 1 shared Alex C.H. LiuiD· 1 shared Andrea ArrudaiD· 1 shared Christopher B. MarshalliD· 1 shared Elise QuadriiD· 1 shared Erwin M. SchoofiD· 1 shared John E. DickiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron David SchimmerORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 12, 2026

CD59 organizes the plasma membrane to sustain oncogenic Ras-MAPK signaling and is a targetable vulnerability in acute myeloid leukemia

Abdula Maher, Dhanoop Manikoth Ayyathan, Séverine Cathelin…·Steven M. Chan

This study identifies CD59 as a critical regulator of Ras-MAPK signaling in AML, showing its depletion impairs leukemic growth and identifies rILYd4 as a potential therapeutic target.

DOI 10.64898/2026.08.11.744285

humanbulk RNA-seq

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