Yixun Su

This study identifies impaired astrocytic Cx43 syncytial networks in the lateral habenula as a driver of adolescent stress-induced depression through disrupted synaptic connectivity and neuronal function.

This study identifies a nuclear function of Cx43 in microglia that restricts neurotoxicity during brain development, revealing a channel-independent mechanism involving transcriptional regulation.

The paper identifies a novel neuron-glia communication mechanism where neurons transfer lysosomes to OPCs, linking this process to neurodegenerative disease progression.

This study identifies microglial connexin43 hemichannels as a therapeutic target for Alzheimer's disease, showing that blocking them reduces pathology and cognitive impairment in mouse models.

This study identifies a network involving oligodendroglial precursors and immune cells that drives early demyelination in EAE, showing that targeting CCL4 disrupts this cycle.

The paper uses single-cell RNA-seq to study liver and gallbladder development from the embryonic endoderm, identifying key transcription factors and gene expression changes during differentiation.