Jianqin Niu

This study identifies impaired astrocytic Cx43 syncytial networks in the lateral habenula as a driver of adolescent stress-induced depression through disrupted synaptic connectivity and neuronal function.

This study identifies a nuclear function of Cx43 in microglia that restricts neurotoxicity during brain development, revealing a channel-independent mechanism involving transcriptional regulation.

The paper identifies a brain-tumour axis linking chronic stress to gastric cancer progression via NPY signalling, showing NPY1R as a therapeutic target.

This study identifies sex-specific mechanisms in major depressive disorder, highlighting impaired neuron-OPC communication and myelination in females.

This study shows that increasing ezrin in astrocytes makes mice more resilient to stress-induced depressive behaviors, while decreasing it increases susceptibility.

The paper identifies a novel neuron-glia communication mechanism where neurons transfer lysosomes to OPCs, linking this process to neurodegenerative disease progression.

This study identifies microglial connexin43 hemichannels as a therapeutic target for Alzheimer's disease, showing that blocking them reduces pathology and cognitive impairment in mouse models.

This study identifies a network involving oligodendroglial precursors and immune cells that drives early demyelination in EAE, showing that targeting CCL4 disrupts this cycle.