Chuchu Wang

Gut Roseburia hominis-derived 10-hydroxystearic acid alleviates metabolic disorder by restoring hepatic fatty acid metabolism

This study identifies Roseburia hominis-derived 10-hydroxystearic acid as a metabolite that improves metabolic health by restoring hepatic fatty acid metabolism in mice.

FeatureMAP enables network-guided interpretation of untargeted metabolomics

FeatureMAP improves interpretation of untargeted metabolomics data by integrating annotation, network refinement, and functional analysis, revealing metabolic patterns in Alzheimer's disease.

A rational design strategy and validation for protease-resistant fusion-inhibitor antiviral peptides

This study designs and validates protease-resistant antiviral peptides that inhibit SARS-CoV-2 fusion, showing improved efficacy in vitro and in vivo.

Leveraging Large Language Models for Redundancy-Aware Pathway Analysis and Deep Biological Interpretation

MAPA uses large language models to reduce redundancy in pathway analysis and improve biological interpretation of multi-omics data.

In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET

This study uses cryo-electron tomography to visualize the in-situ structure and topography of AMPA receptor scaffolding complexes at molecular resolution.

Deep Learning-based Pseudo-Mass Spectrometry Imaging Analysis for Precision Medicine

The paper introduces deepPseudoMSI, a deep learning framework that converts LC-MS data into pseudo-MS images for improved disease diagnosis in precision medicine.

massDatabase: utilities for the operation of the public compound and pathway database

massDatabase provides an R package for streamlined compound annotation and pathway enrichment analysis by integrating public compound and pathway databases.

TidyMass: An Object-oriented Reproducible Analysis Framework for LC-MS Data

tidyMass provides a reproducible and shareable framework for LC-MS metabolomics data analysis.