Author
Washington University in St. LouisORCID 0000-0001-8238-9782Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tim J. Vickers, David P. Buckley, Nazia Khatoon…·James M. Fleckenstein
This study shows that parenteral vaccination with recombinant EtpA glycoprotein can protect against ETEC intestinal colonization in mice, with protection dependent on vaccination schedule and adjuvant type.
Zachary T. Berndsen, Marjahan Akhtar, Mahima Thapa…·James M. Fleckenstein
This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.
Alaullah Sheikh, Debayan Ganguli, Tim J. Vickers…·James M. Fleckenstein
The paper shows that host-derived CEACAM-laden vesicles capture ETEC and its toxins, reducing pathogen load and neutralizing toxins during infection.