Author

Marjahan Akhtar

Washington University in St. LouisORCID 0000-0001-8316-9191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alaullah SheikhiD· 2 shared James M. FleckensteiniD· 2 shared Nazia KhatooniD· 2 shared Tim J. VickersiD· 2 shared Aaron J. SchmitziD· 1 shared Ali H. EllebedyiD· 1 shared Andrew B. WardiD· 1 shared Bernhard B. SingeriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Alaullah SheikhORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin

Zachary T. Berndsen, Marjahan Akhtar, Mahima Thapa, Tim J. Vickers, Aaron J. Schmitz, Jonathan L. Torres, Sabyasachi Baboo, Pardeep Kumar, Nazia Khatoon, Alaullah Sheikh, Melissa Hamrick, Jolene K. Diedrich, Salvador Martínez‐Bartolomé, Patrick T. Garrett, John R. Yates, , James M. Fleckenstein

This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.

PLoS Pathogens · Sep 16, 2024Peer-reviewedMicrobiology

Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization.

Alaullah Sheikh, Debayan Ganguli, Tim J. Vickers, Bernhard B. Singer, Jennifer D. Foulke-Abel, Marjahan Akhtar, Nazia Khatoon, Bipul Setu, Supratim Basu, Clayton D. Harro, Nicole Maier, Wandy L. Beatty, Subhra Chakraborty, Taufiqur Rahman Bhuiyan, Firdausi Qadri, , James M. Fleckenstein

The paper shows that host-derived CEACAM-laden vesicles capture ETEC and its toxins, reducing pathogen load and neutralizing toxins during infection.

Proceedings of the National Academy of Sciences · Sep 12, 2024Peer-reviewedMicrobiology