Author

Angelo Lombardo

Vita-Salute San Raffaele UniversityORCID 0000-0001-8262-042XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandra Maria MartoranaiD· 1 shared Alessandra PolissiiD· 1 shared Alessandro MigliaraiD· 1 shared Anna CelantiD· 1 shared Davide CittaroiD· 1 shared F Colnaghi· 1 shared Francesca GranucciiD· 1 shared Giampiero PietrocolaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alessandra Maria MartoranaORCID

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2 papers

Recent·Most cited

Mechanoreceptors initiate innate immunity in response to microbial infections

Giulia Stucchi, Marco Galli, S Cozzi, Anna Celant, Laura Marongiu, Giuseppe Rocca, F Colnaghi, Maria Rita Chelazzi, Alessandra Polissi, Alessandra Maria Martorana, Giampiero Pietrocola, Marina Vai, Ivan Orlandi, Renato Ostuni, Simona Barresi, , Francesca Granucci

The paper reveals a two-tier mechanism of neutrophil recruitment during infections, where mechanosensing initiates innate immunity through PIEZO1 channels and LTB4 production.

Nature Immunology · Sep 9, 2026Peer-reviewedImmunology

In vitro selection of Engineered Transcriptional Repressors for targeted epigenetic silencing and initial evaluation of their specificity profile

Alessandro Migliara, Martino Alfredo Cappelluti, Sara Valsoni, Ivan Merelli, Davide Cittaro, Angelo Lombardo

The paper describes an in vitro screening protocol to identify effective gRNAs for epigenetic silencing using engineered transcriptional repressors and evaluates their genome-wide specificity.

bioRxiv · Aug 30, 2022 · PreprintSynthetic Biology