Author

Giuseppe Rocca

University of Milano-BicoccaORCID 0000-0002-4825-6748Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Francesca GranucciiD· 3 shared Agnieszka Katarzyna MaciołaiD· 2 shared Alfredo Pherez-FarahiD· 2 shared Edoardo PeroniiD· 2 shared Enrico Dotta· 2 shared Gioia BoncompagniiD· 2 shared Giulia PasqualiD· 2 shared Tania BaccegaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

Francesca GranucciORCID

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3 papers

Recent·Most cited

Sequential engagement of distinct dendritic cell subsets shapes Th2 polarization

Enrico Dotta, Nathan Sébastien Zangger, Giulia Cesaro, Giuseppe Rocca, Edoardo Peroni, Alfredo Pherez-Farah, Agnieszka Katarzyna Macioła, Weisha Qi, Tania Baccega, Gioia Boncompagni, Michelle Guarniero, Giacomo Baruzzo, Francesca Granucci, Barbara Di Camillo, Annette Oxenius, Giulia Pasqual

The paper shows that distinct dendritic cell subsets sequentially engage CD4 T cells during priming, with late CD70 DC2s driving Th2 polarization.

bioRxiv · Oct 21, 2026 · PreprintImmunology

Antigen recognition licenses therapeutic CD8+ T cells to organize a multicellular myeloid interaction network in the tumor microenvironment

Alfredo Pherez-Farah, Willem de Koning, Weisha Qi, Gioia Boncompagni, Enrico Dotta, Edoardo Peroni, Tania Baccega, Agnieszka Katarzyna Macioła, Giuseppe Rocca, Greta Maria Paola Giordano Attianese, Francesca Granucci, Melita B. Irving, Andew Stubbs, Giulia Pasqual

This study investigates how therapeutic CD8+ T cells interact with myeloid cells in the tumor microenvironment through antigen recognition, revealing state-selective networks and the role of pMHC-I sources.

bioRxiv · Oct 20, 2026 · PreprintImmunology

Mechanoreceptors initiate innate immunity in response to microbial infections

Giulia Stucchi, Marco Galli, S Cozzi, Anna Celant, Laura Marongiu, Giuseppe Rocca, F Colnaghi, Maria Rita Chelazzi, Alessandra Polissi, Alessandra Maria Martorana, Giampiero Pietrocola, Marina Vai, Ivan Orlandi, Renato Ostuni, Simona Barresi, , Francesca Granucci

The paper reveals a two-tier mechanism of neutrophil recruitment during infections, where mechanosensing initiates innate immunity through PIEZO1 channels and LTB4 production.

Nature Immunology · Sep 9, 2026Peer-reviewedImmunology