Author

Sara Valsoni

The San Raffaele Telethon Institute for Gene TherapyORCID 0000-0002-0512-1376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Andrea BianchiiD· 2 shared Chiara LanzuoloiD· 2 shared Endre SebestyéniD· 2 shared Federica LuciniiD· 2 shared Francesco FerrariiD· 2 shared Ivan MerelliiD· 2 shared Alessandro MigliaraiD· 1 shared Amélie GerschiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Andrea BianchiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 23, 2023

CD32 allows capturing blood cells emergence in slow motion during human embryonic development

Rebecca Scarfò, Monah Abou Alezz, Mahassen El Khoury…·Andrea Ditadi

The paper identifies CD32 as a marker for hemogenic endothelial cells in human embryos and shows its role in hematopoietic commitment.

DOI 10.1101/2023.03.23.530597

humanbulk RNA-seq

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintAug 30, 2022

In vitro selection of Engineered Transcriptional Repressors for targeted epigenetic silencing and initial evaluation of their specificity profile

Alessandro Migliara, Martino Alfredo Cappelluti, Sara Valsoni…·Angelo Lombardo

The paper describes an in vitro screening protocol to identify effective gRNAs for epigenetic silencing using engineered transcriptional repressors and evaluates their genome-wide specificity.

1 citation

humanCRISPR screen

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Molecular BiologyNature CommunicationsPeer-reviewedDec 8, 2020

Early Polycomb-target deregulations in Hutchinson-Gilford Progeria Syndrome revealed by heterochromatin analysis

Endre Sebestyén, Fabrizia Marullo, Federica Lucini…·Chiara Lanzuolo

The paper identifies early chromatin structural changes in HGPS using a new method, showing Polycomb target gene deregulation linked to lamin-associated domain disruption.

49 citations

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 19, 2020

A ChIC solution for ChIP-seq quality assessment

Carmen Maria Livi, Ilario Tagliaferri, Koustav Pal…·Francesco Ferrari

The paper introduces ChIC, a ChIP-seq quality assessment framework that evaluates enrichment profile shape, providing a reliable score for data quality.

1 citation

ChIP-seqmachine learning (classical)

𝕏 PostBluesky