Simone Altmann

The paper uses MOT-library profiling to assess all possible mutations at a drug binding site and predicts resistance mechanisms through computational modeling.

The paper identifies mutations in trypanosome CPSF3 that confer resistance to acoziborole, a drug targeting RNA processing, and explains the molecular mechanism of resistance through computational modeling.

The paper identifies a novel aphid-specific effector family, CHL, associated with avirulence through differential expression and structural analysis.

The paper uses multi-omics approaches to identify aphid effector candidates linked to virulence and avirulence in pea aphids on Medicago truncatula.