Xiuli Yang

This study shows that vascular smooth muscle cell loss, not amyloidosis or neuroinflammation, causes cerebrovascular reactivity impairment in Alzheimer's disease.

This study examines the spatiotemporal relationship between microstructural injury and cerebral perfusion after intracerebral hemorrhage in mice, finding dissociation between diffusion and perfusion responses.

This study identifies microglial Lag3 as a key receptor linking extracellular α-synuclein PFF recognition to neurotoxic astrocyte conversion and dopaminergic neurodegeneration.

The paper identifies microbleeds as a specific marker of amyloid-related vascular injury in 5xFAD mice, distinct from small-vessel disease.

This study characterizes hyperintense signals in pCASL MRI of mice, showing they appear in arteries, veins, and ventricles, differing from humans, and identifies optimal PLD and crusher gradient settings for accurate CBF measurement.

This study introduces a bidirectional crusher gradient method to estimate labeling efficiency in pCASL MRI for mice, finding typical efficiencies of 0.780 +/- 0.048.

The paper shows a copper-containing nanozyme worsens alpha-synucleinopathy by increasing nitrosative stress, while a copper-free version reduces pathology in neurodegenerative models.

This study shows neuronal LAG3 is essential for α-synuclein propagation and neurodegeneration in Parkinson's disease, suggesting LAG3 as a therapeutic target.

This study examines vascular responses to hypercapnia in mice, showing that 5 minutes of 5% CO2 is sufficient for 95% CBF increase but recovery takes longer than the built-up phase.

This study identifies key factors affecting cerebral blood flow measurement accuracy using phase contrast MRI and provides guidelines for optimal settings.

This study investigates factors affecting T2 measurement reliability in MRI using Monte Carlo simulations and finds that SNR, TE range, and repetition number influence reproducibility.

This study identifies Lag3 as a neuronal receptor for Tau preformed fibrils, essential for their uptake, propagation, and transmission in Tauopathies.

This study shows that neural stem cells reduce BBB permeability and brain edema after ICH in rats by inhibiting MAPK pathways.