David M. MacLean

This study assesses the impact of AMPA receptor subunit type, alternative splicing, and auxiliary proteins on trafficking using high-throughput methods, finding subunit type as the most significant factor.

This study shows that proline substitutions in the ASIC1 β11-12 linker significantly slow desensitization, with minimal effects on activation and ion selectivity.

The paper shows that I-2 promotes PP1γ positive regulation of synaptic transmission in hippocampal neurons through enhanced interaction with neurabin.

The paper investigates the role of β11-12 linker isomerization in ASIC desensitization and recovery using electrophysiology, simulations, and cross-linking.