Kohei Otomo

This paper introduces a data-driven correction framework to account for axial- and radial-position-dependent intensity attenuation in 3D fluorescence microscopy of C. elegans embryos, improving quantitative accuracy.

This paper develops an implantable microprism interface for deep-brain imaging with submicrometer resolution and wide-field two-photon microscopy.

This study investigates how Aβ dimers alter fast and localized calcium elevations in astrocytes, finding increased frequency and occupancy of calcium events mediated by P2Y1 receptors and ER Ca2+ release.

This study examines how photothermal therapy affects ERK signaling and intercellular communication in tumor spheroids using FRET sensors and deep learning.

The paper develops a deep-learning-based pipeline for segmenting and tracking cells in 3D brain imaging data, achieving high accuracy across different conditions and datasets.