Author

Wesam Bassiouni

University of AlbertaORCID 0000-0001-8410-3960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Amit P. BhavsariD· 1 shared Bridgette HartleyiD· 1 shared En-Hung AiiD· 1 shared Khaled S. Abd‐ElrahmaniD· 1 shared Maria J. Spavor· 1 shared Michèle G. DuValiD· 1 shared Moahmed Abdelnaby· 1 shared Olivier JulieniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Amit P. BhavsarORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintAug 26, 2026

Restoring neurovascular coupling in Alzheimer's disease tauopathy through M1 mAChR modulation

Wesam Bassiouni, Moahmed Abdelnaby, En-Hung Ai, Khaled S. Abd‐Elrahman

This study shows that activating M1 mAChR with VU0486846 restores neurovascular coupling deficits in tauopathy mice, with sex-specific effects.

DOI 10.64898/2026.08.18.745579

mouseexperimental assay

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Pharmacology & ToxicologybioRxivPreprintMar 3, 2026

Matrix metalloproteinases proteolyze RAB proteins and contribute to cisplatin-induced ototoxicity

Zahra Zandi, Bridgette Hartley, Wesam Bassiouni…·Amit P. Bhavsar

This study shows MMP-2 and MMP-9 contribute to cisplatin-induced ototoxicity by cleaving RAB proteins, and inhibiting them improves hair cell survival.

DOI 10.64898/2026.02.28.708770

mouseproteomics

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