Michael T. Craig

The paper investigates whether AD-like pathology affects thalamic projections to the retrosplenial cortex in hAPP-J20 mice, finding no impairment in synaptic strength or c-Fos expression.

This study shows glucocorticoids regulate perineuronal net component gene expression and parvalbumin in mouse cortical neurons, with effects varying by developmental stage.

This study investigates neuroinflammation in mice driven by TLR7 activation, finding global immune activation and region-specific neuronal gene expression changes in mood-related brain areas.

This study investigates synaptic inputs to the retrosplenial cortex, finding that all recorded pyramidal neurons receive input from the anterior thalamic nuclei, with stronger responses compared to other sources.

This study identifies thalamostriatal circuit disruption as a conserved neuroinflammatory mechanism linking systemic inflammation to depression and anhedonia in humans and mice.

The paper investigates a reported projection from mouse anterior cingulate cortex to hippocampus and finds no evidence of such a direct connection using multiple methods.

This study examines network impairments in APPNL-G-F mice during sleep, finding NREM-specific changes in mPFC spindles and hippocampal SWRs linked to PV interneuron dysfunction.

The paper investigates the synaptic connections of the nucleus reuniens to hippocampal CA1 and finds that it preferentially targets inhibitory interneurons rather than pyramidal cells.

The paper tests if chemogenetic activation of thalamic nuclei improves memory in Alzheimer's mouse models but finds no significant improvement in spatial memory or hyperactivity.