Author

Kirstyn Gardner-Stephen

University of GlasgowORCID 0000-0003-2796-9017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Deepika SharmaiD· 3 shared Jennifer A. BarrieiD· 3 shared John J ColeiD· 3 shared Jonathan CavanaghiD· 3 shared Lilya AndrianovaiD· 2 shared Megan Saathoff· 2 shared Michael T. CraigiD· 2 shared Rhona McGonigaliD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Deepika SharmaORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 6, 2025

Macrophages drive inguinal fat pad and lymph node remodelling in response to peripheral inflammation.

Robin Bartolini, Deepika Sharma, Gillian J. Wilson…·Gerard J. Graham

This study shows that peripheral inflammation triggers fat pad atrophy and lymph node expansion via macrophage activity, supporting immune response energy needs.

DOI 10.1101/2025.10.06.680668

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 25, 2025

Neuroinflammation driven by TLR7 activation in mice results in a global inflammatory response driving circuit-specific changes in neuronal gene expression

Kirstyn Gardner-Stephen, Robin J Carvajal-Quisilema, Lilya Andrianova…·Jonathan Cavanagh

This study investigates neuroinflammation in mice driven by TLR7 activation, finding global immune activation and region-specific neuronal gene expression changes in mood-related brain areas.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 26, 2024

Psoriasis-related neuroinflammation disrupts thalamostriatal signalling driving anhedonia in both humans and mice

Deepika Sharma, Lilya Andrianova, Rhona McGonigal…·Jonathan Cavanagh

This study identifies thalamostriatal circuit disruption as a conserved neuroinflammatory mechanism linking systemic inflammation to depression and anhedonia in humans and mice.

1 citation

humanmouse

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