Jing Yang

This study shows that stromal gasdermin D-mediated pyroptosis promotes CD4⁺ T-cell remodeling in Tet2-deficient hematopoiesis by creating a feedback loop between stromal cells and immune cells.

The paper introduces an automated system for high-throughput proteomic data generation, demonstrating its robustness and application in spatial proteomics and plasma/cell line profiling.

This paper introduces Integral-Hyperplex, a method combining isobaric tags and tandem mass tags to increase single-cell proteomics throughput by 30-fold, validated through quantification experiments and automated labeling.

pChem assesses chemoproteomic probe performance by evaluating modification-homogeneity, profiling efficiency, and residue selectivity using isotopically coded probe-derived modifications.