Maria R. Conte

This study identifies a pre-rRNA positive feedback loop driven by CK2 in the nucleolus that promotes malignant ribosome biogenesis and cancer growth.

This study uses cryo-EM to reveal drebrin's structural interaction with F-actin through two domains, explaining its modulatory role in actin networks and competitive binding with other proteins.

The paper identifies rDNA sequence variants associated with human traits using UK Biobank data, finding enrichment in body size traits within the 28S rRNA Expansion Segment 15L region.

This study identifies an intrinsically disordered region in LARP6 that restricts conformational flexibility of the La-module, enabling RNA-binding selectivity and promoting cancer cell viability and invasion.

The paper identifies a conserved region in LARP4 that interacts with RACK1 to enhance translation of specific mRNAs.