Author

Emilie L. Alard

Queen Mary University of LondonORCID 0000-0002-7804-4121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Faraz K. MardakhehiD· 3 shared Martin DodeliD· 2 shared Audrey LumeauiD· 1 shared David W. J. McQuarrieiD· 1 shared Eric E. O’NeilliD· 1 shared FB CopleyiD· 1 shared Ferenc MülleriD· 1 shared Giancarlo AbisiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

Faraz K. MardakhehORCID

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3 papers

Recent·Most cited

LARP1-DM15/Sgt is a reader for cap-adjacent 2`-O-ribose methylation in TOP ribosomal protein mRNAs required for localization to synapses

Yuan W. Tian, Yavor Hadzhiev, Giancarlo Abis, Martin Dodel, Emilie L. Alard, David W. J. McQuarrie, Faraz K. Mardakheh, Maria Conte, Ferenc Müller, Matthias Soller

bioRxiv · Sep 18, 2026 · PreprintMolecular Biology

A pre-rRNA positive feedback loop drives malignant ribosome biogenesis

Emilie L. Alard, Martin Dodel, Shannon N. Russell, Zeinab Rekad, Maximilian F. Wiesbeck, Maia Cooper, Zaynah Patel, Muhammad S. Azman, Maria R. Conte, Stefan H. Stricker, Keaton Ian Jones, Eric E. O’Neill, Faraz K. Mardakheh

This study identifies a pre-rRNA positive feedback loop driven by CK2 in the nucleolus that promotes malignant ribosome biogenesis and cancer growth.

bioRxiv · Jul 3, 2026 · PreprintCancer Biology

High levels of DNA replication initiation factors indicate ATR inhibitor sensitivity via excessive origin firing

Audrey Lumeau, Pauline Luise Pfuderer, S De Angelis, James A. Scarth, Molly A Guscott, Nadeem Shaikh, FB Copley, Henry Gerdes, Emilie L. Alard, Pedro R. Cutillas, Faraz K. Mardakheh, Michael A. Boemo, Josep V. Forment, Sarah Elizabeth McClelland

This study identifies that high levels of DNA replication initiation factors correlate with ATR inhibitor sensitivity due to excessive origin firing in cancer cells.

bioRxiv · Feb 27, 2025 · PreprintCancer Biology