G Xu

TMEformer is a spatial deep learning framework that models tumor microenvironment dependencies and enables virtual perturbation analysis using spatial transcriptomics data.

This paper introduces two novel 19F NMR probes to study tyrosine ring-flip dynamics in proteins, showing they can quantify and modulate these motions in vitro and in living cells.

This paper identifies two circular RNA aptamers that act as sub-stoichiometric chaperones to suppress pathological TDP-43 condensation and rescue splicing and motor dysfunction in vivo.