Natalia Mendelev

Single-nucleus multiomic analysis reveals modulation of the gene regulatory circuit landscape in pituitary cell types during mouse estrous cycle.

The paper uses single-nucleus multiomics to study pituitary cell changes during the mouse estrous cycle, finding stage-dependent gene regulatory circuits and validated ETS2-driven gene expression patterns.

Regulation of murine follicle-stimulating hormone β subunit transcription by newly identified enhancers

The paper identifies four activin-sensitive enhancers upstream of the murine Fshb gene, showing differential regulation by SMAD2/3 and FOXL2 in gonadotropes.

Consensus Pituitary Atlas, a scalable resource for annotation, novel marker discovery and analyses in pituitary gland research

The paper creates a large-scale Consensus Pituitary Atlas to improve reproducibility and enable marker discovery and analysis in pituitary research.

Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise

The paper uses single-nucleus multiome sequencing to analyze gene regulatory changes in human skeletal muscle after endurance exercise, identifying fiber-type specific regulatory programs and transcription factor networks.

Acute and Chronic Molecular Signatures and Associated Symptoms of Blast Exposure in Military Breachers

This study identifies acute and chronic molecular changes in military breachers exposed to blast, showing transcriptional and inflammatory biomarkers for acute exposure and DNA methylation for chronic symptoms.

Brain-derived circulating cell-free DNA defines the brain region and cell specific origins associated with neuronal atrophy

The paper identifies brain-derived circulating cell-free DNA as a peripheral biomarker specific to cell-type and brain-region origins in neurotrauma and neurodegeneration.