Author

Siddhartha M. Sharma

The Jackson Laboratory for Genomic MedicineORCID 0000-0001-8597-7547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Duygu UcariD· 2 shared Neerja KatiyariD· 2 shared Ron KorstanjeiD· 2 shared Ahrim YouniD· 1 shared Aisha AnsariD· 1 shared Alok V. JoglekariD· 1 shared Ana María ArbeláeziD· 1 shared Anthony N. VomundiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Duygu UcarORCID

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3 papers

Recent·Most cited

ImmunologyNature ImmunologyPeer-reviewedNov 28, 2025

A microenvironment-driven, HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes

Neetu Srivastava, Anthony N. Vomund, Rongzhen Yu…·Xiaoxiao Wan

The paper identifies a microenvironment-driven neoantigen, C19S, in type 1 diabetes that activates persistent memory T cells through HLA-DQ8 recognition.

15 citationstop 2%

humanproteomics

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GenomicsbioRxivPreprintOct 20, 2023

Comprehensive single cell aging atlas of mammary tissues reveals shared epigenomic and transcriptomic signatures of aging and cancer

Brittany Lynn Angarola, Siddhartha M. Sharma, Neerja Katiyar…·Olga Anczuków

This study creates a single-cell aging atlas of mouse mammary tissues, identifying shared epigenomic and transcriptomic changes between aging and cancer.

2 citations

mousescRNA-seq

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Systems BiologyAging CellPeer-reviewedFeb 24, 2023

Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging

Emin Onur Karakaslar, Neerja Katiyar, Muneer G. Hasham…·Duygu Ucar

The paper identifies the transcriptional activation of Jun and Fos genes in the AP-1 complex as a conserved aging signature in immune cells, contributing to inflammaging across mouse strains and humans.

98 citationstop 2%

mouseATAC-seq

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