Olga Anczuków

This study shows that ultraconserved poison exons regulate mitotic splicing fidelity and stem cell viability by controlling SR protein levels and splicing networks.

This study shows that bacterial species and individual donors differentially modulate airway gene expression and alternative splicing in human epithelial cells.

SpliceDecoder prioritizes biologically meaningful splicing events by predicting their impact on transcript productivity, protein sequence, and functional domains.

The paper identifies intron retention in STAT2 as a regulator of immune signaling and a predictor of immunotherapy response in lung cancer.

The paper examines TE-driven alternative splicing in breast cancer using long-read RNA sequencing, identifying tumor-specific splicing events and TE-derived isoforms with potential therapeutic implications.

This study uses spatial transcriptomics and deep learning to analyze melanoma treatment resistance, identifying persister states and resistance mechanisms with spatiotemporal resolution.

The paper shows that alternative splicing is coupled to gene expression in a subset of variably expressed genes across multiple tissues.

Cellos is a high-throughput image analysis pipeline for 3D organoid segmentation and analysis, enabling accurate quantification of drug responses and cell interactions in cancer organoids.

This study creates a single-cell aging atlas of mouse mammary tissues, identifying shared epigenomic and transcriptomic changes between aging and cancer.

The paper uses long-read RNA sequencing to identify novel isoforms in breast cancer, finding splicing events associated with patient survival.

The paper identifies sex-biased differential alternative splicing across multiple human tissues and links it to gene function and estrogen response.

This paper introduces HBA-DEALS, a method that simultaneously identifies differential expression and splicing, showing genes can have differential expression, splicing, both, or neither.