Yasmina Cuartero

This study shows that EWS-FLI1 expression in human embryonic mesenchymal stem cells leads to an ES-like transcriptome and tumor formation, despite not preferentially binding promoters.

The paper identifies Hormone-Control Regions (HCRs) that organize genome structure and mediate opposing transcriptional responses to steroid hormones in breast cancer cells.

OneD improves Hi-C reproducibility for samples with abnormal karyotypes by addressing copy number variations, outperforming existing methods while maintaining performance on normal karyotypes.

The paper shows transcription factors drive genome topology changes before gene expression during cell reprogramming.

The paper compares two Hi-C samples, showing how adherence to FAIR principles leads to successful sequencing projects.