Author

Hsin-An Shih

Institute of Biological Chemistry, Academia SinicaORCID 0000-0001-8613-0700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jessica Y. C. Huang· 1 shared Kuen‐Phon WuiD· 1 shared Ming-Chieh Tsai· 1 shared Piotr DrączkowskiiD· 1 shared Rosa VineriD· 1 shared Shang‐Te Danny HsuiD· 1 shared Shu‐Yu LiniD· 1 shared Steven LiniD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Jessica Y. C. Huang

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 15, 2025

Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome

Piotr Drączkowski, Szu-Ni Chen, Ting Chen…·Shang‐Te Danny Hsu

The paper reports cryo-EM structures of the human 26S proteasome bound to K11/K48-branched ubiquitin chains, revealing a multivalent recognition mechanism involving new binding sites for K11 and alternating K11-K48 linkages.

21 citationstop 2%

humancryo-EM

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