Author

Jessica Y. C. Huang

Institute of Biological Chemistry, Academia Sinica

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:structural biology· 1

Frequent Co-Authors

Kuen‐Phon WuiD· 2 shared Hsin-An ShihiD· 1 shared Ming-Chieh Tsai· 1 shared Piotr DrączkowskiiD· 1 shared Rosa VineriD· 1 shared Shang‐Te Danny HsuiD· 1 shared Shu‐Yu LiniD· 1 shared Steven LiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Kuen‐Phon WuORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMar 17, 2026

Calcium modulates intramolecular long-range contacts to form a polymorphic α-synuclein A53T fibril

Jessica Y. C. Huang, Kuen‐Phon Wu

This study investigates how calcium ions affect the structure and aggregation of the A53T mutant of α-synuclein, revealing structural changes in fibril formation.

DOI 10.64898/2026.03.14.711779

humanstructural biology

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BiochemistryNature CommunicationsPeer-reviewedOct 15, 2025

Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome

Piotr Drączkowski, Szu-Ni Chen, Ting Chen…·Shang‐Te Danny Hsu

The paper reports cryo-EM structures of the human 26S proteasome bound to K11/K48-branched ubiquitin chains, revealing a multivalent recognition mechanism involving new binding sites for K11 and alternating K11-K48 linkages.

21 citationstop 2%

humancryo-EM

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