Author

Fausto J. Rodríguez

Johns Hopkins UniversityORCID 0000-0001-8662-1219Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Swati DubeyiD· 2 shared Ajeeth Iyer· 1 shared Albert LaiiD· 1 shared Charles G. EberhartiD· 1 shared Christopher Tse· 1 shared David A. NathansoniD· 1 shared Fabiola Guillen· 1 shared Guanqiao Yu· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Swati DubeyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 4, 2025

Beyond Cell Cycle Control: CDKN2A Loss Orchestrates NAD⁺ Metabolic Plasticity and NAMPT Inhibitor Sensitivity in Glioblastoma

Swati Dubey, Guanqiao Yu, Ryana Aboul-Hosn…·Fausto J. Rodríguez

The paper shows CDKN2A loss in glioblastoma affects NAD+ metabolism and increases sensitivity to NAMPT inhibitors, beyond its role in cell cycle control.

DOI 10.64898/2025.12.02.691903

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintDec 14, 2024

High-Throughput Targeted Drug Screening for NF1-associated High-Grade Gliomas with ATRX Deficiency

Swati Dubey, Simran Rai, Fabiola Guillen…·Fausto J. Rodríguez

This study identifies K784-6195 as a selective cytotoxic compound for NF1-associated high-grade gliomas with ATRX deficiency, showing reduced sensitivity in wild-type ATRX cells and metabolic pathway disruption.

1 citation

humanproteomics

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