Patrick Van Dijck

This study investigates the role of Ato proteins in carboxylic acid utilization in Candida albicans, revealing functional diversity and regulatory interactions among Ato family members.

The paper identifies and characterizes new hybrid peptide-polyketide-specialized lipid biosynthesis pathways in bacteria, revealing novel metabolites with functional properties.

This study investigates the synergistic effects of ethanolic extract of propolis with antifungal agents against Candida species, finding synergies with amphotericin B and additivity with nystatin.

This study shows that increased nuclear SnRK11 activity in Arabidopsis reduces sink strength, thereby delaying clubroot development by repressing sucrose transporter and cell wall invertase expression and activity.

This study shows lactate enhances iron assimilation in C. albicans by modulating iron transporter gene expression and promoting iron accumulation under iron-limited conditions.

This study identifies riboflavin production by vaginal lactobacilli and shows its role in modulating host immune responses and redox balance.

The paper investigates how Erg3 loss-of-function contributes to echinocandin resistance in Candida species by analyzing combined mutations in ERG3 and FKS2.

This study shows that the ATO gene family in Candida albicans is essential for acetate uptake and gut colonization, highlighting its role in fungal adaptation to the gut environment.

The paper identifies hyper-multidrug-resistant Nakaseomyces glabratus strains with fitness trade-offs and explores nitroxoline as a potential alternative therapy for resistant UTIs.

This study identifies trehalose as a mediator of fluconazole tolerance in C. glabrata by altering sterol composition, showing that trehalose deficiency reduces drug tolerance.

This study compares four CRISPR-Cas9 systems for genome editing in Candida auris, finding significant differences in efficiency and integration patterns.

This study compares sphingolipid profiles of fluconazole-resistant Candidozyma auris isolates to identify intra-clade lipid compositional differences linked to antifungal resistance.

The paper identifies Als5 and Scf1 as complementary adhesins in Candida auris that promote cell-cell interaction and biofilm formation through functional redundancy.

This paper identifies the riboflavin biosynthetic pathway as a novel antifungal target in Candida species, showing that key enzymes are essential and that riboflavin uptake mechanisms differ among species.

The paper generates an ORFeome collection and associated tools for studying Candida albicans pathogenesis.