Spyridoula Karamanou A

The paper constructs genome-reduced strains of S. lividans to enhance heterologous protein secretion, finding improved secretion levels and altered metabolic and stress responses.

The paper shows how EndophilinA couples calcium influx to synaptic autophagy and identifies a Parkinson-risk mutation that disrupts this process.

The paper introduces PyHDX, a tool for analyzing HDX-MS data to compute residue-level Gibbs free energy across protein conditions and homologues.

The paper investigates the structural dynamics of SctV, a component of the Type III translocase export gate in E. coli, revealing its conformational changes and interactions with chaperones and ATPase.