Choong H. Lee

This study uses multi-parametric MRI to improve myelin mapping in developing mouse brains, finding that T2 imaging is the strongest predictor of myelin content.

This study shows that RBM8A is essential for bone development and Hedgehog signaling, with its deficiency causing skeletal defects and impaired endochondral ossification.

This study shows that NFI proteins regulate radial glial progenitor lifespan and output in a dose-dependent manner, affecting neocortical development and causing malformations in human cerebral organoids and mouse models.

The paper develops a 3D developmental common coordinate framework (DevCCF) for mouse brains across multiple developmental stages to enable data integration and analysis of brain development.