Jiangyang Zhang

This study uses multi-parametric MRI to improve myelin mapping in developing mouse brains, finding that T2 imaging is the strongest predictor of myelin content.

This study quantifies inter-scanner variability in mouse brain MRI using phantoms and ex vivo specimens, finding small differences in ADC, volume, and quantitative maps.

FiberLM improves mouse brain tractography by reducing false connections and aligning with viral tracer data using a Transformer model trained on Allen Mouse Brain Connectivity Atlas data.

This study shows that RBM8A is essential for bone development and Hedgehog signaling, with its deficiency causing skeletal defects and impaired endochondral ossification.

This paper introduces TRFS, a non-invasive brain stimulation technique using RF energy to modulate neural activity and behavior in mice, showing both suppression and excitation effects depending on the mode.

This study shows that NFI proteins regulate radial glial progenitor lifespan and output in a dose-dependent manner, affecting neocortical development and causing malformations in human cerebral organoids and mouse models.

The paper develops a low-dimensional manifold representation to estimate brain age and identify structural aging trajectories from neuroimaging data.

This paper develops a relaxation-selective IVIM technique to assess fluid compartments and aging effects in the human choroid plexus using MRI in middle-aged to elderly and young participants.

This paper demonstrates the feasibility of using T1-D and T2-D MRI to detect incoherent CSF flows in the human brain using IVIM methods.

This study uses a pig model to assess long-term post-concussion brain changes using volumetric and diffusion tensor imaging after mild traumatic brain injury.

The paper presents a multimodal, multiscale atlas of the mouse brain and head with high-resolution histology and co-registered MRI data, enabling better integration of molecular and connectivity data.

The paper develops a 3D developmental common coordinate framework (DevCCF) for mouse brains across multiple developmental stages to enable data integration and analysis of brain development.

This study shows that ablating cerebellar output neurons has less impact on behavior than genetic mutations in these neurons, which cause additional deficits in learning and memory.

The paper introduces an open-source 3D-printable animal conditioning platform for preclinical brain imaging in awake and anesthetized mice and rats, demonstrating its use across multiple imaging modalities.

This study uses multi-parametric MRI to detect enhanced myelination in Gli1-/- mice, showing that combining T2, T1/T2, and radial diffusivity explains 80% of MBP variance in the corpus callosum.

This study shows that early-life adversity impairs reelin-positive projections from the LEC to the dorsal hippocampus in male mice, leading to contextual memory deficits and structural changes.

This paper uses computational modeling to show that early adversity increases stochasticity in the formation of structural brain networks in mice.

This study uses MRI to identify meningeal inflammation in a mouse model of multiple sclerosis and shows that BTK inhibition reduces inflammation.

This study shows that canonical Wnt signaling regulates patterning, differentiation, and nucleogenesis in mouse hypothalamus and prethalamus, with defects observed in both gain and loss of function mutations.