Xujie Liu

This study optimizes gene knockout in hPSCs using an inducible Cas9 system and identifies effective sgRNAs by comparing experimental results with cleavage efficiency algorithms.

This paper describes a method to generate high-purity, scalable human iPSC-derived cardiomyocytes using a bioreactor, showing improved viability, function, and consistency compared to traditional methods.

This study identifies PALMD as a Z-line-associated protein that mitigates cardiac injury through stabilization of NEXN using in vivo proximity proteomics.

This study identifies RBPMS2 as a conserved regulator of alternative splicing that supports myofibril organization and calcium handling in cardiomyocytes across species.