Roberto Nitsch

The paper introduces INDUCE-seq, a method to accurately detect both endogenous and induced DNA double strand breaks, overcoming limitations of existing methods.

This paper introduces an inducible CRISPR-Cas9 system for preclinical drug discovery, enabling controlled genome editing in mice to model cancer and test therapies.

The paper introduces VIVO, a method to detect off-target mutations from in vivo CRISPR-Cas editing, showing that well-designed gRNAs can edit efficiently without detectable off-targets.