Author

Mick D. Fellows

AstraZeneca (United Kingdom)ORCID 0000-0002-0300-0132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:CRISPR screen· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Roberto NitschiD· 2 shared Alba CarrerasiD· 1 shared Felix M. Dobbs· 1 shared Frank SeeligeriD· 1 shared J. Keith JoungiD· 1 shared Jimmy A. GuoiD· 1 shared Jose Malagon-Lopez· 1 shared Kendell ClementiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Roberto NitschORCID

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2 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJul 9, 2022

Precision digital mapping of endogenous andinduced genomic DNA breaks by INDUCE-seq

Felix M. Dobbs, Patrick van Eijk, Mick D. Fellows…·Simon Huw Reed

The paper introduces INDUCE-seq, a method to accurately detect both endogenous and induced DNA double strand breaks, overcoming limitations of existing methods.

39 citations

whole-genome sequencingexperimental assay

Molecular BiologyNaturePeer-reviewedSep 1, 2018

In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations

Pınar Akçakaya, Maggie L. Bobbin, Jimmy A. Guo…·J. Keith Joung

The paper introduces VIVO, a method to detect off-target mutations from in vivo CRISPR-Cas editing, showing that well-designed gRNAs can edit efficiently without detectable off-targets.

322 citationstop 1%

humanCRISPR screen