GenomicsCell ReportsPeer-reviewed
CTCF mediated genome architecture regulates the dosage of mitotically stable mono-allelic expression of autosomal genes
Keerthivasan Raanin Chandradoss, Bindia Chawla, Shivnarayan Dhuppar…·Kuljeet Singh Sandhu
The paper shows that CTCF-mediated chromatin loops create genomic insulation that enables mono-allelic expression of autosomal genes and protects their dosage from fluctuations.
5 citations