Rajesh Ramachandran

TECPR2 is a Rab5 effector that regulates endosomal cargo recycling

This study identifies TECPR2 as a Rab5 effector involved in endosomal cargo recycling, showing its role in integrin recycling and its loss-of-function effects in zebrafish.

Regulation of the lncRNA malat1/Egr1 Axis by Wnt, Notch and TGF-β signaling: A Key Mechanism in Retina Regeneration

This study identifies the malat1/Egr1 axis regulated by Wnt, Notch, and TGF-β signaling as critical for retina regeneration in zebrafish, with species-specific regulation of talam1 observed between zebrafish and mice.

YY1 protein is essential for the promotion of Muller glia reprogramming and retina regeneration

This study identifies YY1's role in zebrafish retina regeneration by showing its regulation of transcription, signaling pathways, and gene expression during Muller glia reprogramming.

CTCF mediated genome architecture regulates the dosage of mitotically stable mono-allelic expression of autosomal genes

The paper shows that CTCF-mediated chromatin loops create genomic insulation that enables mono-allelic expression of autosomal genes and protects their dosage from fluctuations.