Author

Stefan V. Jovinge

Van Andel InstituteORCID 0000-0002-8446-0228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Eric J. KortiD· 2 shared Matthew J. WeilandiD· 2 shared Bryan A. KillingeriD· 1 shared Catherine E. KeltyiD· 1 shared Chun LiuiD· 1 shared Edgars GrinsiD· 1 shared Elizabeth EnsinkiD· 1 shared Emily Eugster· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersGenomics

Eric J. KortORCID

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Author profile →

3 papers

Recent·Most cited

Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotective

Lee L. Marshall, Bryan A. Killinger, Elizabeth Ensink, Peipei Li, Katie X. Li, Wei Cui, Noah Lubben, Matthew J. Weiland, Xinhe Wang, Juozas Gordevičius, Gerhard A. Coetzee, Jiyan Ma, Stefan V. Jovinge, Viviane Labrie

The paper identifies increased TET2 expression as a driver of epigenetic dysregulation in Parkinson’s disease neurons and shows that reducing Tet2 activity is neuroprotective in mice.

Nature Neuroscience · Aug 17, 2020Peer-reviewedNeuroscience

The inflammasome of circulatory collapse: single cell analysis of survival on extracorporeal life support.

Eric J. Kort, Matthew J. Weiland, Edgars Grins, Emily Eugster, Hsiao-yun Milliron, Catherine E. Kelty, Nabin Manandhar Shrestha, Tomasz A. Timek, Marzia Leacche, Stephen J. Fitch, Theodore J. Boeve, Greg Marco, Michael G. Dickinson, Penny Wilton, Stefan V. Jovinge

The paper uses single-cell RNA sequencing to identify CD8+/CD52+ NKT cells as a survival predictor in patients on VA-ECLS, showing their inverse correlation with IL-6 production.

bioRxiv · Mar 7, 2020 · PreprintGenomics

Toxicogenomic identification of repositioned therapy for a monogenic disease

Eric J. Kort, Nazish Sayed, Chun Liu, Sean M. Wu, Joseph C. Wu, Stefan V. Jovinge

The paper uses transcriptomic data to identify potential drug therapies for a monogenic disease by finding FDA-approved drugs with similar transcriptional profiles.

bioRxiv · Sep 23, 2019 · PreprintGenomics