Rebecca R. Bellone

The paper introduces a comprehensive equine allele-specific expression resource using integrated RNA sequencing and histone modification data from four Thoroughbreds across nine tissues.

This paper presents a comprehensive functional annotation of the horse genome, addressing limitations in current RNA-seq and comparative genomics approaches by integrating data from nine major tissues.

The paper improves the equine transcriptome annotation using long-read RNA sequencing, achieving 45% better completeness and enhanced identification of alternative splicing and noncoding genes.

This paper develops epigenetic clocks for horses using DNA methylation data from multiple tissues, showing age-related CpGs are near developmental genes and that castration does not significantly affect aging rate.

The paper uses machine learning to show that transcription predicts histone marks and chromatin states, and that transcription is required for maintaining active and repressive histone modifications.

The paper presents an updated horse reference genome, EquCab3, which improves contiguity and composition compared to the previous version, EquCab2.