Montserrat Barragán

This study shows that Nlrp5-null oocytes have reduced DNMT3L and impaired de novo methylation, leading to imprinting disorders and developmental issues.

The paper uses single-cell proteomics to show that advanced maternal age oocytes have reduced proteostasis and meiosis proteins.

This study analyzes the transcriptomes of human oocytes at different maturation stages and finds that age affects specific gene pathways in matured oocytes.