Author

Ibrahim Shehata Elmadbouh

University of MinnesotaORCID 0000-0001-8892-124XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Aleksandra BabichevaiD· 2 shared Christina M. PabelickiD· 2 shared Jason X.‐J. YuaniD· 2 shared Y. S. PrakashiD· 2 shared Amin Izadi· 1 shared Ayako MakinoiD· 1 shared Cole Paquin· 1 shared Jian WangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Aleksandra BabichevaORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintOct 14, 2025

Loss of miRNA-153 promotes endothelial-to-mesenchymal transition and compromises lung vascular integrity

Ibrahim Shehata Elmadbouh, Zhunran Zhong, Li Wang…·Aleksandra Babicheva

This study shows that loss of miR-153 promotes EndMT in lung endothelial cells, leading to vascular permeability and remodeling in pulmonary hypertension.

DOI 10.1101/2025.10.14.682369

humanbulk RNA-seq

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Cell BiologyAmerican Journal of Physiology-Lung Cellular and Molecular PhysiologyPeer-reviewedMay 7, 2025

Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells

Aleksandra Babicheva, Ibrahim Shehata Elmadbouh, Shanshan Song…·Jason X.‐J. Yuan

This study shows that TGF-β1-induced endothelial-to-mesenchymal transition in human lung vascular endothelial cells is Ca²⁺-dependent through store-operated Ca²⁺ entry via STIM1/Orai1 channels.

7 citations

humanexperimental assay

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