Loss of miRNA-153 promotes endothelial-to-mesenchymal transition and compromises lung vascular integrity
Ibrahim Shehata Elmadbouh, Zhunran Zhong, Li Wang, Michael David Thompson, Luke H. Hoeppner, Y. S. Prakash, Jason X.‐J. Yuan, Christina M. Pabelick, Aleksandra Babicheva
This study shows that loss of miR-153 promotes EndMT in lung endothelial cells, leading to vascular permeability and remodeling in pulmonary hypertension.
bioRxiv · Oct 14, 2025 · PreprintPhysiology