Author

Aleksandra Babicheva

University of MinnesotaORCID 0000-0002-0152-2121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Christina M. PabelickiD· 2 shared Ibrahim Shehata ElmadbouhiD· 2 shared Jason X.‐J. YuaniD· 2 shared Y. S. PrakashiD· 2 shared Amin Izadi· 1 shared Ayako MakinoiD· 1 shared Cole Paquin· 1 shared Jian WangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Christina M. PabelickORCID

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2 papers

Recent·Most cited

Loss of miRNA-153 promotes endothelial-to-mesenchymal transition and compromises lung vascular integrity

Ibrahim Shehata Elmadbouh, Zhunran Zhong, Li Wang, Michael David Thompson, Luke H. Hoeppner, Y. S. Prakash, Jason X.‐J. Yuan, Christina M. Pabelick, Aleksandra Babicheva

This study shows that loss of miR-153 promotes EndMT in lung endothelial cells, leading to vascular permeability and remodeling in pulmonary hypertension.

bioRxiv · Oct 14, 2025 · PreprintPhysiology

Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells

Aleksandra Babicheva, Ibrahim Shehata Elmadbouh, Shanshan Song, Michael A Thompson, Ryan Powers, Pritesh Jain, Amin Izadi, Jiyuan Chen, Lauren Yung, Sophia Parmisano, Cole Paquin, Wei‐Ting Wang, Yuqin Chen, Ting Wang, Mona Alotaibi, , Jason X.‐J. Yuan

This study shows that TGF-β1-induced endothelial-to-mesenchymal transition in human lung vascular endothelial cells is Ca²⁺-dependent through store-operated Ca²⁺ entry via STIM1/Orai1 channels.

American Journal of Physiology-Lung Cellular and Molecular Physiology · May 7, 2025Peer-reviewedCell Biology